Drug Information

Drug General Information
Drug ID
DX5ZNT
Drug Name
(S)-3-{2-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid methylamide
Synonyms
CHEMBL3085290
Indication Discovery agent Investigative [1587926]
Formula
C27H34ClN5O2
Canonical SMILES
CNC(=O)N1CCC[C@@H](CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35)C1
InChI
InChI=1S/C27H34ClN5O2/c1-29-27(35)33-11-3-4-19(18-33)16-24(34)31-12-14-32(15-13-31)26-23-9-8-22(28)17-21(23)7-6-20-5-2-10-30-25(20)26/h2,5,8-10,17,19,26H,3-4,6-7,11-16,18H2,1H3,(H,29,35)/t19-,26?/m0/s1
InChIKey
VSCLPVCMHBLNNY-SXMXNQBWSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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