Drug Information

Drug General Information
Drug ID
DX6NDG
Drug Name
4-{5-[4-(3-Chloro-phenyl)-3-oxo-piperazin-1-ylmethyl]-imidazol-1-ylmethyl}-2-(5,6,7,8-tetrahydro-naphthalen-2-yloxy)-benzonitrile
Synonyms
CHEMBL29769
Indication Discovery agent Investigative [1587926]
Formula
C32H30ClN5O2
Canonical SMILES
Clc1cccc(c1)N2CCN(Cc3cncn3Cc4ccc(C#N)c(Oc5ccc6CCCCc6c5)c4)CC2=O
InChI
InChI=1S/C32H30ClN5O2/c33-27-6-3-7-28(16-27)38-13-12-36(21-32(38)39)20-29-18-35-22-37(29)19-23-8-9-26(17-34)31(14-23)40-30-11-10-24-4-1-2-5-25(24)15-30/h3,6-11,14-16,18,22H,1-2,4-5,12-13,19-21H2
InChIKey
DRVXNKXBSICBHX-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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