| Drug General Information |
| Drug ID |
DX6PRB
|
| Drug Name |
3-amino-N-(furan-2-ylmethyl)-5-oxo-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide
|
| Synonyms |
CHEMBL1431996
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Formula |
C17H15N3O3S
|
| Canonical SMILES |
Nc1c(sc2nc3CCCC(=O)c3cc12)C(=O)NCc4occc4
|
| InChI |
InChI=1S/C17H15N3O3S/c18-14-11-7-10-12(4-1-5-13(10)21)20-17(11)24-15(14)16(22)19-8-9-3-2-6-23-9/h2-3,6-7H,1,4-5,8,18H2,(H,19,22)
|
| InChIKey |
IRDVCTIKJACDIY-UHFFFAOYSA-N
|
| Target and Pathway |
| Target(s) |
Estrogen receptor beta |
Target Info |
|
[1]
|
|---|
| Induced myeloid leukemia cell differentiation protein Mcl-1 |
Target Info |
|
[1]
|
|
KEGG Pathway
|
Estrogen signaling pathway
|
|
Prolactin signaling pathwayhsa04151:PI3K-Akt signaling pathway
|
|
MicroRNAs in cancer
|
|
NetPath Pathway
|
TCR Signaling Pathway
|
|
PANTHER Pathway
|
Apoptosis signaling pathway
|
|
CCKR signaling map ST
|
|
Pathway Interaction Database
|
Plasma membrane estrogen receptor signaling
|
|
Validated nuclear estrogen receptor beta network
|
|
Validated nuclear estrogen receptor alpha networke2f_pathway:E2F transcription factor network
|
|
Direct p53 effectors
|
|
IL6-mediated signaling events
|
|
HIF-1-alpha transcription factor network
|
|
Reactome
|
Nuclear Receptor transcription pathway
|
|
WikiPathways
|
SIDS Susceptibility Pathways
|
|
Ovarian Infertility Genes
|
|
Integrated Pancreatic Cancer Pathway
|
|
Nuclear ReceptorsWP254:Apoptosis
|
|
miR-targeted genes in muscle cell - TarBase
|
|
miR-targeted genes in lymphocytes - TarBase
|
|
miR-targeted genes in leukocytes - TarBase
|
|
Apoptosis Modulation and Signaling
|
| References |
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 |
|---|
