Drug Information

Drug General Information
Drug ID
DX7TFZ
Drug Name
methyl 1-(3-(5-(ethylcarbamoyl)-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carboxamido)propyl)-4-phenylpiperidine-4-carboxylate
Synonyms
CHEMBL357681
Indication Discovery agent Investigative [1587926]
Formula
C33H41N5O6
Canonical SMILES
CCNC(=O)C1=C(C)NC(=C(C1c2ccc(cc2)[N+](=O)[O-])C(=O)NCCCN3CCC(CC3)(C(=O)OC)c4ccccc4)C
InChI
InChI=1S/C33H41N5O6/c1-5-34-30(39)27-22(2)36-23(3)28(29(27)24-12-14-26(15-13-24)38(42)43)31(40)35-18-9-19-37-20-16-33(17-21-37,32(41)44-4)25-10-7-6-8-11-25/h6-8,10-15,29,36H,5,9,16-21H2,1-4H3,(H,34,39)(H,35,40)
InChIKey
COYXUFNFFWVLGI-UHFFFAOYSA-N
Target and Pathway
Target(s) Alpha-1 adrenergic receptor Target Info [1587926]
Histamine H1 receptor Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
PANTHER Pathway Histamine H1 receptor mediated signaling pathway
Reactome Histamine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
IL-4 Signaling Pathway
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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