Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8NZ1
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| Drug Name |
MIDOSTAURIN
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| Synonyms |
PKC-412; CHEMBL608533
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C35H30N4O4
|
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| Canonical SMILES |
CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35)N(C)C(=O)c9ccccc9
|
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| InChI |
InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1
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| InChIKey |
BMGQWWVMWDBQGC-IIFHNQTCSA-N
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| Target and Pathway | |||||
| Target(s) | FL cytokine receptor | Target Info | [1587926] | ||
| Macrophage colony-stimulating factor 1 | Target Info | [1587926] | |||
| KEGG Pathway | Cytokine-cytokine receptor interaction | ||||
| Hematopoietic cell lineage | |||||
| Pathways in cancer | |||||
| Transcriptional misregulation in cancer | |||||
| Acute myeloid leukemia | |||||
| Central carbon metabolism in cancerhsa04014:Ras signaling pathway | |||||
| Rap1 signaling pathway | |||||
| PI3K-Akt signaling pathway | |||||
| Osteoclast differentiation | |||||
| TNF signaling pathway | |||||
| Rheumatoid arthritis | |||||
| Pathway Interaction Database | Signaling events mediated by PTP1B | ||||
| Signaling events mediated by TCPTP | |||||
| Integrins in angiogenesis | |||||
| References | |||||
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