Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8SLG
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| Drug Name |
7-[(furan-3-yl)carbonyl]-19-methyl-3-(2-methylpropyl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one
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| Synonyms |
CHEMBL411520
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H26N4O3
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| Canonical SMILES |
CC(C)Cn1c2ccc(cc2c3c4CNC(=O)c4c5c(CCc6nn(C)cc56)c13)C(=O)c7cocc7
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| InChI |
InChI=1S/C29H26N4O3/c1-15(2)12-33-23-7-4-16(28(34)17-8-9-36-14-17)10-19(23)25-20-11-30-29(35)26(20)24-18(27(25)33)5-6-22-21(24)13-32(3)31-22/h4,7-10,13-15H,5-6,11-12H2,1-3H3,(H,30,35)
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| InChIKey |
UZJOKMBHGDSKOM-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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