Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX9HRP
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| Drug Name |
9-Cyclopentyl-6-(2-{4-[2-(4-methyl-piperazin-1-yl)-ethoxy]-benzyloxy}-phenylamino)-9H-purine-2-carbonitrile
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| Synonyms |
CHEMBL189730
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C31H36N8O2
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| Canonical SMILES |
CN1CCN(CCOc2ccc(COc3ccccc3Nc4nc(nc5c4ncn5C6CCCC6)C#N)cc2)CC1
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| InChI |
InChI=1S/C31H36N8O2/c1-37-14-16-38(17-15-37)18-19-40-25-12-10-23(11-13-25)21-41-27-9-5-4-8-26(27)34-30-29-31(36-28(20-32)35-30)39(22-33-29)24-6-2-3-7-24/h4-5,8-13,22,24H,2-3,6-7,14-19,21H2,1H3,(H,34,35,36)
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| InChIKey |
WAQLYLNMWXUBCF-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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