Drug Information

Drug General Information
Drug ID
DX9LV8
Drug Name
(20R)-14-chloro-19,20,21,22-tetrahydro-19-oxo-17H-18,20-etheno-6,10:12,16-dimetheno-16H-imidazo[3,4-h][1,8,11,14]oxatriazacycloeicosine-9-carbonitrile
Synonyms
CHEMBL524352
Indication Discovery agent Investigative [1587926]
Formula
C23H20ClN5O2
Canonical SMILES
Clc1cc2CN3CC[C@@H](NCc4cncn4Cc5ccc(C#N)c(Oc(c1)c2)c5)C3=O
InChI
InChI=1S/C23H20ClN5O2/c24-18-5-16-6-20(8-18)31-22-7-15(1-2-17(22)9-25)12-29-14-26-10-19(29)11-27-21-3-4-28(13-16)23(21)30/h1-2,5-8,10,14,21,27H,3-4,11-13H2/t21-/m1/s1
InChIKey
HHCUIUUICDIYLM-OAQYLSRUSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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