Drug Information

Drug General Information
Drug ID
DX9OVI
Drug Name
4-{2-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid phenyl ester
Synonyms
CHEMBL354131
Indication Discovery agent Investigative [1587926]
Formula
C32H34BrClN4O3
Canonical SMILES
Clc1ccc2C(N3CCN(CC3)C(=O)CC4CCN(CC4)C(=O)Oc5ccccc5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C32H34BrClN4O3/c33-25-19-24-7-6-23-20-26(34)8-9-28(23)31(30(24)35-21-25)37-16-14-36(15-17-37)29(39)18-22-10-12-38(13-11-22)32(40)41-27-4-2-1-3-5-27/h1-5,8-9,19-22,31H,6-7,10-18H2
InChIKey
PHLAKICDEGLMTH-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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