Drug Information

Drug General Information
Drug ID
DX9YYH
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-[2-(3H-imidazol-4-yl)-ethyl]-N'-cyano-piperidine-1-carboxamidine
Synonyms
CHEMBL348110
Indication Discovery agent Investigative [1587926]
Formula
C26H25BrClN7
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)\\C(=N/CCc4c[nH]cn4)\\NC#N)c5ncc(Br)cc5CCc2c1
InChI
InChI=1S/C26H25BrClN7/c27-20-11-19-2-1-18-12-21(28)3-4-23(18)24(25(19)32-13-20)17-6-9-35(10-7-17)26(33-15-29)31-8-5-22-14-30-16-34-22/h3-4,11-14,16H,1-2,5-10H2,(H,30,34)(H,31,33)
InChIKey
MZKNCHCTZBSPNY-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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