Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXA07R
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| Drug Name |
(S)-N-(3-(3-(1,3,4-thiadiazol-2-yl)phenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)benzamide
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| Synonyms |
CHEMBL559880
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C20H17N5O2S
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| Canonical SMILES |
O=C(NCC#N)[C@H](Cc1cccc(c1)c2nncs2)NC(=O)c3ccccc3
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| InChI |
InChI=1S/C20H17N5O2S/c21-9-10-22-19(27)17(24-18(26)15-6-2-1-3-7-15)12-14-5-4-8-16(11-14)20-25-23-13-28-20/h1-8,11,13,17H,10,12H2,(H,22,27)(H,24,26)/t17-/m0/s1
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| InChIKey |
AVUGRCORGNXBOQ-KRWDZBQOSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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