Drug Information

Drug General Information
Drug ID
DXA2AV
Drug Name
(S)-2-{[5-(5-Bromo-furan-2-ylmethoxymethyl)-2'-methyl-biphenyl-2-carbonyl]-amino}-4-methylsulfanyl-butyric acid methyl ester
Synonyms
CHEMBL430296
Indication Discovery agent Investigative [1587926]
Formula
C26H28BrNO5S
Canonical SMILES
COC(=O)[C@H](CCSC)NC(=O)c1ccc(COCc2oc(Br)cc2)cc1c3ccccc3C
InChI
InChI=1S/C26H28BrNO5S/c1-17-6-4-5-7-20(17)22-14-18(15-32-16-19-9-11-24(27)33-19)8-10-21(22)25(29)28-23(12-13-34-3)26(30)31-2/h4-11,14,23H,12-13,15-16H2,1-3H3,(H,28,29)/t23-/m0/s1
InChIKey
GPHWYYSELXGMGI-QHCPKHFHSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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