Drug Information

Drug General Information
Drug ID
DXA5IP
Drug Name
4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carboxylic acid (1-methyl-piperidin-4-yl)-amide
Synonyms
CHEMBL171210
Indication Discovery agent Investigative [1587926]
Formula
C25H32ClN5O
Canonical SMILES
CN1CCC(CC1)NC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35
InChI
InChI=1S/C25H32ClN5O/c1-29-11-8-21(9-12-29)28-25(32)31-15-13-30(14-16-31)24-22-7-6-20(26)17-19(22)5-4-18-3-2-10-27-23(18)24/h2-3,6-7,10,17,21,24H,4-5,8-9,11-16H2,1H3,(H,28,32)
InChIKey
FOQJAZUXBJJJLX-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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