Drug Information
| Drug General Information | |||||
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| Drug ID |
DXA9ES
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| Drug Name |
7-[(1E)-1-(ethoxyimino)-2-methylpropyl]-19-methyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one
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| Synonyms |
CHEMBL257794
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H27N5O2
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| Canonical SMILES |
CCO\\N=C(/C(C)C)\\c1ccc2[nH]c3c4CCc5nn(C)cc5c4c6C(=O)NCc6c3c2c1
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| InChI |
InChI=1S/C26H27N5O2/c1-5-33-30-24(13(2)3)14-6-8-19-16(10-14)22-17-11-27-26(32)23(17)21-15(25(22)28-19)7-9-20-18(21)12-31(4)29-20/h6,8,10,12-13,28H,5,7,9,11H2,1-4H3,(H,27,32)/b30-24+
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| InChIKey |
YJQJSZIDTDMDQM-BGABXYSRSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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