Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXB2XL
|
||||
| Drug Name |
(S)-N-(3-cyclohexyl-1-oxo-1-(2-(4-(trifluoromethoxy)phenylamino)ethylamino)propan-2-yl)furan-2-carboxamide
|
||||
| Synonyms |
CHEMBL217496
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H28F3N3O4
|
||||
| Canonical SMILES |
FC(F)(F)Oc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c3occc3)cc1
|
||||
| InChI |
InChI=1S/C23H28F3N3O4/c24-23(25,26)33-18-10-8-17(9-11-18)27-12-13-28-21(30)19(15-16-5-2-1-3-6-16)29-22(31)20-7-4-14-32-20/h4,7-11,14,16,19,27H,1-3,5-6,12-13,15H2,(H,28,30)(H,29,31)/t19-/m0/s1
|
||||
| InChIKey |
ICZBEHKZUOAGHK-IBGZPJMESA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.