Drug Information

Drug General Information
Drug ID
DXB7R9
Drug Name
1-[4-(3-Cyclopropyl-10-methoxy-8-methyl-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone
Synonyms
CHEMBL54352
Indication Discovery agent Investigative [1587926]
Formula
C31H35N3O3
Canonical SMILES
COc1cc(C)cc2CCc3cc(cnc3C(C4CCN(CC4)C(=O)Cc5cc[n+]([O-])cc5)c12)C6CC6
InChI
InChI=1S/C31H35N3O3/c1-20-15-24-5-6-25-18-26(22-3-4-22)19-32-31(25)30(29(24)27(16-20)37-2)23-9-11-33(12-10-23)28(35)17-21-7-13-34(36)14-8-21/h7-8,13-16,18-19,22-23,30H,3-6,9-12,17H2,1-2H3
InChIKey
IGWXEAQPLLHTRJ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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