Drug Information
| Drug General Information | |||||
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| Drug ID |
DXB8AZ
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| Drug Name |
N-(4-phenoxyphenyl)-3-(3-(4-(3,4,5-trimethoxyphenylamino)-1,3,5-triazin-2-yl)pyridin-2-ylamino)benzamide
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| Synonyms |
CHEMBL220540
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C36H31N7O5
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| Canonical SMILES |
COc1cc(Nc2ncnc(n2)c3cccnc3Nc4cccc(c4)C(=O)Nc5ccc(Oc6ccccc6)cc5)cc(OC)c1OC
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| InChI |
InChI=1S/C36H31N7O5/c1-45-30-20-26(21-31(46-2)32(30)47-3)42-36-39-22-38-34(43-36)29-13-8-18-37-33(29)40-25-10-7-9-23(19-25)35(44)41-24-14-16-28(17-15-24)48-27-11-5-4-6-12-27/h4-22H,1-3H3,(H,37,40)(H,41,44)(H,38,39,42,43)
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| InChIKey |
BRXKGRHLVVRORC-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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