Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXB8S8
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| Drug Name |
(E/Z)-4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vinyl)pyrimidin-2-amine
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| Synonyms |
CHEMBL497114
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C17H13N5S
|
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| Canonical SMILES |
Nc1nccc(\\C=C\\c2c(nc3sccn23)c4ccccc4)n1
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| InChI |
InChI=1S/C17H13N5S/c18-16-19-9-8-13(20-16)6-7-14-15(12-4-2-1-3-5-12)21-17-22(14)10-11-23-17/h1-11H,(H2,18,19,20)/b7-6+
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| InChIKey |
GOJZHNWOESVAEU-VOTSOKGWSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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