Drug Information

Drug General Information
Drug ID
DXBT1E
Drug Name
(2S)-methyl 2-(2-(3-(2-(1H-imidazol-5-yl)ethyl)-5-methyl-5-(naphthalen-1-yl)-2,4-dioxoimidazolidin-1-yl)acetamido)-4-(methylthio)butanoate
Synonyms
CHEMBL203951
Indication Discovery agent Investigative [1587926]
Formula
C27H31N5O5S
Canonical SMILES
COC(=O)[C@H](CCSC)NC(=O)CN1C(=O)N(CCc2c[nH]cn2)C(=O)C1(C)c3cccc4ccccc34
InChI
InChI=1S/C27H31N5O5S/c1-27(21-10-6-8-18-7-4-5-9-20(18)21)25(35)31(13-11-19-15-28-17-29-19)26(36)32(27)16-23(33)30-22(12-14-38-3)24(34)37-2/h4-10,15,17,22H,11-14,16H2,1-3H3,(H,28,29)(H,30,33)/t22-,27?/m0/s1
InChIKey
RXGRTVPDLCLHHK-YMQLSTQVSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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