Drug Information
Drug General Information | |||||
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Drug ID |
DXC4LC
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Drug Name |
4-methyl-3-(3-(pyrimidin-4-yl)pyridin-2-yloxy)-N-(3-(trifluoromethyl)phenyl)benzamide
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Synonyms |
CHEMBL218425
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Indication | Discovery agent | Investigative | [1587926] | ||
Formula |
C24H17F3N4O2
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Canonical SMILES |
Cc1ccc(cc1Oc2ncccc2c3ccncn3)C(=O)Nc4cccc(c4)C(F)(F)F
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InChI |
InChI=1S/C24H17F3N4O2/c1-15-7-8-16(22(32)31-18-5-2-4-17(13-18)24(25,26)27)12-21(15)33-23-19(6-3-10-29-23)20-9-11-28-14-30-20/h2-14H,1H3,(H,31,32)
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InChIKey |
PSDTVRBCPBZBIK-UHFFFAOYSA-N
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Target and Pathway | |||||
Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
Angiopoietin 1 receptor | Target Info | [1587926] | |||
NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
PANTHER Pathway | Angiogenesis | ||||
VEGF signaling pathwayP00005:Angiogenesis | |||||
Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
Beta3 integrin cell surface interactions | |||||
Signaling events mediated by TCPTP | |||||
SHP2 signaling | |||||
S1P1 pathway | |||||
VEGF and VEGFR signaling network | |||||
Integrins in angiogenesis | |||||
Signaling events mediated by VEGFR1 and VEGFR2 | |||||
Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
References |
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