Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
DXD2HJ
|
||||
Drug Name |
(S)-N-((1S,2S,4R)-6-Acetoxy-1-benzyl-2-hydroxy-4-isobutylcarbamoyl-hexyl)-2-(3-methyl-butyrylamino)-succinamic acid
|
||||
Synonyms |
CHEMBL154897
|
||||
Indication | Discovery agent | Investigative | [1] | ||
Formula |
C29H45N3O8
|
||||
Canonical SMILES |
CC(C)CNC(=O)[C@H](CCOC(=O)C)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)C[C@H](NC(=O)CC(C)C)C(=O)O
|
||||
InChI |
InChI=1S/C29H45N3O8/c1-18(2)13-26(35)32-24(29(38)39)16-27(36)31-23(14-21-9-7-6-8-10-21)25(34)15-22(11-12-40-20(5)33)28(37)30-17-19(3)4/h6-10,18-19,22-25,34H,11-17H2,1-5H3,(H,30,37)(H,31,36)(H,32,35)(H,38,39)/t22-,23+,24+,25+/m1/s1
|
||||
InChIKey |
FQFQVINPQPAWNY-ROHNOIKCSA-N
|
||||
Target and Pathway | |||||
Target(s) | Renin, renal | Target Info | [1] | ||
Cathepsin D | Target Info | [1] | |||
BioCyc Pathway | Thyroid hormone biosynthesis | ||||
KEGG Pathway | Renin-angiotensin systemhsa04071:Sphingolipid signaling pathway | ||||
Lysosome | |||||
Tuberculosis | |||||
NetPath Pathway | IL2 Signaling Pathway | ||||
Pathway Interaction Database | LKB1 signaling events | ||||
Ceramide signaling pathway | |||||
Direct p53 effectors | |||||
Validated nuclear estrogen receptor alpha network | |||||
PathWhiz Pathway | Angiotensin Metabolism | ||||
Reactome | Metabolism of Angiotensinogen to AngiotensinsR-HSA-1442490:Collagen degradation | ||||
Metabolism of Angiotensinogen to Angiotensins | |||||
MHC class II antigen presentation | |||||
WikiPathways | ACE Inhibitor Pathway | ||||
Metabolism of Angiotensinogen to Angiotensins | |||||
References | |||||
REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.