Drug Information

Drug General Information
Drug ID
DXE1OM
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(4-(3-iodo-propyl)-phenyl)-N'-cyano-piperidine-1-carboxamidine
Synonyms
CHEMBL156431
Indication Discovery agent Investigative [1587926]
Formula
C30H29BrClN5
Canonical SMILES
CC(C)c1ccc(N\\C(=N/C#N)\\N2CCC(=C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)CC2)cc1
InChI
InChI=1S/C30H29BrClN5/c1-19(2)20-5-8-26(9-6-20)36-30(35-18-33)37-13-11-21(12-14-37)28-27-10-7-25(32)16-22(27)3-4-23-15-24(31)17-34-29(23)28/h5-10,15-17,19H,3-4,11-14H2,1-2H3,(H,35,36)
InChIKey
CQCSPZLJLKEHSA-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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