Drug Information

Drug General Information
Drug ID
DXE4RF
Drug Name
N-Isopropyl-2-[2-(2-methoxy-phenyl)-1H-indol-3-yl]-N-pyridin-4-ylmethyl-acetamide
Synonyms
CHEMBL169817
Indication Discovery agent Investigative [1587926]
Formula
C26H27N3O2
Canonical SMILES
COc1ccccc1c2[nH]c3ccccc3c2CC(=O)N(Cc4ccncc4)C(C)C
InChI
InChI=1S/C26H27N3O2/c1-18(2)29(17-19-12-14-27-15-13-19)25(30)16-22-20-8-4-6-10-23(20)28-26(22)21-9-5-7-11-24(21)31-3/h4-15,18,28H,16-17H2,1-3H3
InChIKey
YNFYLZQERVSRSE-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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