Drug Information

Drug General Information
Drug ID
DXE7FK
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(3-imidazol-1-yl-propyl)-N'-cyano-piperidine-1-carboxamidine
Synonyms
CHEMBL347625
Indication Discovery agent Investigative [1587926]
Formula
C27H27BrClN7
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)\\C(=N/CCCn4ccnc4)\\NC#N)c5ncc(Br)cc5CCc2c1
InChI
InChI=1S/C27H27BrClN7/c28-22-14-21-3-2-20-15-23(29)4-5-24(20)25(26(21)33-16-22)19-6-11-36(12-7-19)27(34-17-30)32-8-1-10-35-13-9-31-18-35/h4-5,9,13-16,18H,1-3,6-8,10-12H2,(H,32,34)
InChIKey
QASVCVNBLBRDBC-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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