Drug Information

Drug General Information
Drug ID
DXE7WG
Drug Name
2-{2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-oxo-ethyl}-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one
Synonyms
CHEMBL317144
Indication Discovery agent Investigative [1587926]
Formula
C28H24ClN3O4S
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)C(=O)CN4C(=O)c5ccccc5S4(=O)=O)c6ncccc6CCc2c1
InChI
InChI=1S/C28H24ClN3O4S/c29-21-9-10-22-20(16-21)8-7-19-4-3-13-30-27(19)26(22)18-11-14-31(15-12-18)25(33)17-32-28(34)23-5-1-2-6-24(23)37(32,35)36/h1-6,9-10,13,16H,7-8,11-12,14-15,17H2
InChIKey
CAUXQDNIEYKVMA-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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