Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXEP4E
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| Drug Name |
N-((S)-1-((R)-2-(benzyloxy)-1-cyanoethylamino)-4-methyl-1-oxopentan-2-yl)-1-methyl-1H-indole-2-carboxamide
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| Synonyms |
CHEMBL208284
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H30N4O3
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)c1cc2ccccc2n1C)C(=O)N[C@@H](COCc3ccccc3)C#N
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| InChI |
InChI=1S/C26H30N4O3/c1-18(2)13-22(29-26(32)24-14-20-11-7-8-12-23(20)30(24)3)25(31)28-21(15-27)17-33-16-19-9-5-4-6-10-19/h4-12,14,18,21-22H,13,16-17H2,1-3H3,(H,28,31)(H,29,32)/t21-,22+/m1/s1
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| InChIKey |
ASGHMQMKSKMSAX-YADHBBJMSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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