Drug Information
| Drug General Information | |||||
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| Drug ID |
DXF5IW
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| Drug Name |
methyl N-(5-(5-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)-1-oxo-2-pyridyloxy)-1H-benzimidazol-2-yl)-carbamate
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| Synonyms |
CHEMBL397757
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H16F4N6O5
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| Canonical SMILES |
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)c[n+]3[O-])cc2[nH]1
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| InChI |
InChI=1S/C22H16F4N6O5/c1-36-21(34)31-19-28-15-6-4-13(9-17(15)29-19)37-18-7-3-12(10-32(18)35)27-20(33)30-16-8-11(22(24,25)26)2-5-14(16)23/h2-10H,1H3,(H2,27,30,33)(H2,28,29,31,34)
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| InChIKey |
XAIJULJJMLLWOQ-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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