Drug Information

Drug General Information
Drug ID
DXG2NJ
Drug Name
1-[(S)-4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-2-(2-methoxy-ethyl)-piperazin-1-yl]-2-piperidin-4-yl-ethanone
Synonyms
CHEMBL170921
Indication Discovery agent Investigative [1587926]
Formula
C28H36BrClN4O2
Canonical SMILES
COCC[C@H]1CN(CCN1C(=O)CC2CCNCC2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35
InChI
InChI=1S/C28H36BrClN4O2/c1-36-13-8-24-18-33(11-12-34(24)26(35)14-19-6-9-31-10-7-19)28-25-5-4-23(30)16-20(25)2-3-21-15-22(29)17-32-27(21)28/h4-5,15-17,19,24,28,31H,2-3,6-14,18H2,1H3/t24-,28?/m0/s1
InChIKey
URWJIGVDAQEIEV-ZZDYIDRTSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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