Drug Information
| Drug General Information | |||||
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| Drug ID |
DXG4TS
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| Drug Name |
N-(6-(4-((2-fluoro-5(trifluoromethyl)phenyl)aminocarbonylamino)phenoxy)-1H-benzimidazol-2-yl)-2-(1H-pyrrol-1-yl)benzamide
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| Synonyms |
CHEMBL243919
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C32H22F4N6O3
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| Canonical SMILES |
Fc1ccc(cc1NC(=O)Nc2ccc(Oc3ccc4nc(NC(=O)c5ccccc5c6ccc[nH]6)[nH]c4c3)cc2)C(F)(F)F
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| InChI |
InChI=1S/C32H22F4N6O3/c33-24-13-7-18(32(34,35)36)16-27(24)41-31(44)38-19-8-10-20(11-9-19)45-21-12-14-26-28(17-21)40-30(39-26)42-29(43)23-5-2-1-4-22(23)25-6-3-15-37-25/h1-17,37H,(H2,38,41,44)(H2,39,40,42,43)
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| InChIKey |
SPDICIKFASBCHA-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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