Drug Information

Drug General Information
Drug ID
DXG8PX
Drug Name
1-[4-(4,8-Dichloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-pyridin-3-yl-ethanone
Synonyms
CHEMBL354221
Indication Discovery agent Investigative [1587926]
Formula
C25H24Cl2N4O
Canonical SMILES
Clc1ccc2C(N3CCN(CC3)C(=O)Cc4cccnc4)c5nccc(Cl)c5CCc2c1
InChI
InChI=1S/C25H24Cl2N4O/c26-19-4-6-20-18(15-19)3-5-21-22(27)7-9-29-24(21)25(20)31-12-10-30(11-13-31)23(32)14-17-2-1-8-28-16-17/h1-2,4,6-9,15-16,25H,3,5,10-14H2
InChIKey
RYESZZWSLBGXMJ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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