Drug Information
| Drug General Information | |||||
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| Drug ID |
DXI9CI
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| Drug Name |
7-[(3-bromothiophen-2-yl)carbonyl]-19-methyl-3-(2-methylpropyl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one
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| Synonyms |
CHEMBL403158
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H25BrN4O2S
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| Canonical SMILES |
CC(C)Cn1c2ccc(cc2c3c4CNC(=O)c4c5c(CCc6nn(C)cc56)c13)C(=O)c7sccc7Br
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| InChI |
InChI=1S/C29H25BrN4O2S/c1-14(2)12-34-22-7-4-15(27(35)28-20(30)8-9-37-28)10-17(22)24-18-11-31-29(36)25(18)23-16(26(24)34)5-6-21-19(23)13-33(3)32-21/h4,7-10,13-14H,5-6,11-12H2,1-3H3,(H,31,36)
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| InChIKey |
NIWZSNQTGBQFMJ-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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