Drug Information

Drug General Information
Drug ID
DXI9DS
Drug Name
1-[4-(8-Chloro-1-oxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-(1-oxy-pyridin-3-yl)-ethanone
Synonyms
CHEMBL171186
Indication Discovery agent Investigative [1587926]
Formula
C25H25ClN4O3
Canonical SMILES
[O-][n+]1cccc(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5ccc[n+]([O-])c35)c1
InChI
InChI=1S/C25H25ClN4O3/c26-21-7-8-22-20(16-21)6-5-19-4-2-10-30(33)24(19)25(22)28-13-11-27(12-14-28)23(31)15-18-3-1-9-29(32)17-18/h1-4,7-10,16-17,25H,5-6,11-15H2
InChIKey
CBKFNXPELRPUMF-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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