Drug Information

Drug General Information
Drug ID
DXJ3IR
Drug Name
4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-[2-(4-chloro-phenyl)-acetyl]-piperazine-2-carboxylic acid methylamide
Synonyms
CHEMBL200851
Indication Discovery agent Investigative [1587926]
Formula
C28H27BrCl2N4O2
Canonical SMILES
CNC(=O)C1CN(CCN1C(=O)Cc2ccc(Cl)cc2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35
InChI
InChI=1S/C28H27BrCl2N4O2/c1-32-28(37)24-16-34(10-11-35(24)25(36)12-17-2-6-21(30)7-3-17)27-23-9-8-22(31)14-18(23)4-5-19-13-20(29)15-33-26(19)27/h2-3,6-9,13-15,24,27H,4-5,10-12,16H2,1H3,(H,32,37)
InChIKey
WYSDEQZPJKRKGQ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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