Drug Information

Drug General Information
Drug ID
DXJ3OL
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-(2-pyridin-4-yl-ethyl)-piperidine-1-carboxamidine
Synonyms
CHEMBL345846
Indication Discovery agent Investigative [1587926]
Formula
C28H26BrClN6
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)\\C(=N/CCc4ccncc4)\\NC#N)c5ncc(Br)cc5CCc2c1
InChI
InChI=1S/C28H26BrClN6/c29-23-15-22-2-1-21-16-24(30)3-4-25(21)26(27(22)34-17-23)20-8-13-36(14-9-20)28(35-18-31)33-12-7-19-5-10-32-11-6-19/h3-6,10-11,15-17H,1-2,7-9,12-14H2,(H,33,35)
InChIKey
WINKJJCYTRJCQK-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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