Drug Information
| Drug General Information | |||||
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| Drug ID |
DXJ4OX
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| Drug Name |
7-acetyl-19-methyl-3-(propan-2-yl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one
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| Synonyms |
CHEMBL255404
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H24N4O2
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| Canonical SMILES |
CC(C)n1c2ccc(cc2c3c4CNC(=O)c4c5c(CCc6nn(C)cc56)c13)C(=O)C
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| InChI |
InChI=1S/C25H24N4O2/c1-12(2)29-20-8-5-14(13(3)30)9-16(20)22-17-10-26-25(31)23(17)21-15(24(22)29)6-7-19-18(21)11-28(4)27-19/h5,8-9,11-12H,6-7,10H2,1-4H3,(H,26,31)
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| InChIKey |
FMIWNLDVSLITSM-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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