Drug Information

Drug General Information
Drug ID
DXK2II
Drug Name
1-{3-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carbonyl]-piperidin-1-yl}-ethanone
Synonyms
CHEMBL353280
Indication Discovery agent Investigative [1587926]
Formula
C26H31ClN4O2
Canonical SMILES
CC(=O)N1CCCC(C1)C(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35
InChI
InChI=1S/C26H31ClN4O2/c1-18(32)31-11-3-5-21(17-31)26(33)30-14-12-29(13-15-30)25-23-9-8-22(27)16-20(23)7-6-19-4-2-10-28-24(19)25/h2,4,8-10,16,21,25H,3,5-7,11-15,17H2,1H3
InChIKey
XIXHYXVYAJENTI-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.