Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXK2UO
|
||||
| Drug Name |
methyl N-(5-(4-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)phenylsulfinyl)-1H-benzimidazol-2-yl)carbamate
|
||||
| Synonyms |
CHEMBL244098
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H17F4N5O4S
|
||||
| Canonical SMILES |
COC(=O)Nc1nc2ccc(cc2[nH]1)[S+]([O-])c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3
|
||||
| InChI |
InChI=1S/C23H17F4N5O4S/c1-36-22(34)32-20-29-17-9-7-15(11-19(17)30-20)37(35)14-5-3-13(4-6-14)28-21(33)31-18-10-12(23(25,26)27)2-8-16(18)24/h2-11H,1H3,(H2,28,31,33)(H2,29,30,32,34)
|
||||
| InChIKey |
ZWWMPZYRVRZFEF-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.