Drug Information

Drug General Information
Drug ID
DXK5YF
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-pentanoyl-piperazine-2-carboxylic acid (3-methyl-isoxazol-5-yl)-amide
Synonyms
CHEMBL202334
Indication Discovery agent Investigative [1587926]
Formula
C28H31BrClN5O3
Canonical SMILES
CCCCC(=O)N1CCN(CC1C(=O)Nc2onc(C)c2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35
InChI
InChI=1S/C28H31BrClN5O3/c1-3-4-5-25(36)35-11-10-34(16-23(35)28(37)32-24-12-17(2)33-38-24)27-22-9-8-21(30)14-18(22)6-7-19-13-20(29)15-31-26(19)27/h8-9,12-15,23,27H,3-7,10-11,16H2,1-2H3,(H,32,37)
InChIKey
CGLDQNAZWLLHQY-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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