Drug General Information
Drug ID
DXM0ZS
Drug Name
N-(4-methyl-2-oxo-2H-chromen-7-yl)acetamide
Synonyms
CHEMBL1951641
Indication Discovery agent Investigative [1587926]
Formula
C12H11NO3
Canonical SMILES
CC(=O)Nc1ccc2C(=CC(=O)Oc2c1)C
InChI
InChI=1S/C12H11NO3/c1-7-5-12(15)16-11-6-9(13-8(2)14)3-4-10(7)11/h3-6H,1-2H3,(H,13,14)
InChIKey
AOVJSWHKUGNIDY-UHFFFAOYSA-N
Target and Pathway
Target(s) Carbonic anhydrase IX Target Info [1587926]
Carbonic anhydrase XII Target Info [1587926]
KEGG Pathway Nitrogen metabolismhsa00910:Nitrogen metabolism
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database HIF-1-alpha transcription factor network
Reactome Regulation of gene expression by Hypoxia-inducible Factor
Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxide
WikiPathways Vitamin D Receptor Pathway
Reversible Hydration of Carbon Dioxide
Regulation of Hypoxia-inducible Factor (HIF) by OxygenWP2770:Reversible Hydration of Carbon Dioxide
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in leukocytes - TarBase
miR-targeted genes in epithelium - TarBase
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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