Drug Information

Drug General Information
Drug ID
DXM2XQ
Drug Name
(S)-2-Amino-1-(4-{2-[4-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidin-1-yl)-propan-1-one
Synonyms
CHEMBL170211
Indication Discovery agent Investigative [1587926]
Formula
C28H36ClN5O2
Canonical SMILES
C[C@H](N)C(=O)N1CCC(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35)CC1
InChI
InChI=1S/C28H36ClN5O2/c1-19(30)28(36)34-11-8-20(9-12-34)17-25(35)32-13-15-33(16-14-32)27-24-7-6-23(29)18-22(24)5-4-21-3-2-10-31-26(21)27/h2-3,6-7,10,18-20,27H,4-5,8-9,11-17,30H2,1H3/t19-,27?/m0/s1
InChIKey
LMUBVYBHYAXIBH-JDEXWRGDSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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