Drug Information

Drug General Information
Drug ID
DXM6R8
Drug Name
6-[(4-Chloro-phenyl)-imidazol-1-yl-methyl]-4-phenyl-1H-quinolin-2-one
Synonyms
CHEMBL55431
Indication Discovery agent Investigative [1587926]
Formula
C25H18ClN3O
Canonical SMILES
Oc1cc(c2ccccc2)c3cc(ccc3n1)C(c4ccc(Cl)cc4)n5ccnc5
InChI
InChI=1S/C25H18ClN3O/c26-20-9-6-18(7-10-20)25(29-13-12-27-16-29)19-8-11-23-22(14-19)21(15-24(30)28-23)17-4-2-1-3-5-17/h1-16,25H,(H,28,30)
InChIKey
RHBIJCCFGBZWIO-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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