Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXM7II
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| Drug Name |
(S)-N-(cyanomethyl)-4-methyl-2-((S)-2,2,2-trifluoro-1-(4-phenoxyphenyl)ethylamino)pentanamide
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| Synonyms |
CHEMBL206913
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H24F3N3O2
|
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| Canonical SMILES |
CC(C)C[C@H](N[C@@H](c1ccc(Oc2ccccc2)cc1)C(F)(F)F)C(=O)NCC#N
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| InChI |
InChI=1S/C22H24F3N3O2/c1-15(2)14-19(21(29)27-13-12-26)28-20(22(23,24)25)16-8-10-18(11-9-16)30-17-6-4-3-5-7-17/h3-11,15,19-20,28H,13-14H2,1-2H3,(H,27,29)/t19-,20-/m0/s1
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| InChIKey |
WLPUAATZDJXQRR-PMACEKPBSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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