Drug Information

Drug General Information
Drug ID
DXM7JG
Drug Name
4-((R)-8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carboxylic acid pyridin-3-ylamide
Synonyms
CHEMBL172154
Indication Discovery agent Investigative [1587926]
Formula
C24H24ClN5O
Canonical SMILES
Clc1ccc2[C@@H](N3CCN(CC3)C(=O)Nc4cccnc4)c5ncccc5CCc2c1
InChI
InChI=1S/C24H24ClN5O/c25-19-7-8-21-18(15-19)6-5-17-3-1-10-27-22(17)23(21)29-11-13-30(14-12-29)24(31)28-20-4-2-9-26-16-20/h1-4,7-10,15-16,23H,5-6,11-14H2,(H,28,31)/t23-/m1/s1
InChIKey
UYAWMLCIDQNGSJ-HSZRJFAPSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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