Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXN4A2
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| Drug Name |
1-(2-Chloro-phenyl)-1H-[1,2,4]triazole-3-carboxylic acid {1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-amide
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| Synonyms |
CHEMBL74142
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H29ClN6O3
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| Canonical SMILES |
COc1ccc(NCCNC(=O)[C@H](CC(C)C)NC(=O)c2ncn(n2)c3ccccc3Cl)cc1
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| InChI |
InChI=1S/C24H29ClN6O3/c1-16(2)14-20(23(32)27-13-12-26-17-8-10-18(34-3)11-9-17)29-24(33)22-28-15-31(30-22)21-7-5-4-6-19(21)25/h4-11,15-16,20,26H,12-14H2,1-3H3,(H,27,32)(H,29,33)/t20-/m0/s1
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| InChIKey |
OXSJNGDTLSLRIV-FQEVSTJZSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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