Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXN83H
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| Drug Name |
2-cyano-4-((cyclohexylmethyl)(methyl)amino)-N-phenethylpyrimidine-5-carboxamide
|
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| Synonyms |
CHEMBL457001
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H27N5O
|
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| Canonical SMILES |
CN(CC1CCCCC1)c2nc(ncc2C(=O)NCCc3ccccc3)C#N
|
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| InChI |
InChI=1S/C22H27N5O/c1-27(16-18-10-6-3-7-11-18)21-19(15-25-20(14-23)26-21)22(28)24-13-12-17-8-4-2-5-9-17/h2,4-5,8-9,15,18H,3,6-7,10-13,16H2,1H3,(H,24,28)
|
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| InChIKey |
UXDKVFLANDNUJE-UHFFFAOYSA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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