Drug Information

Drug General Information
Drug ID
DXP7YM
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cyclopentylamide 2-[(pyridin-3-ylmethyl)-amide]
Synonyms
CHEMBL383764
Indication Discovery agent Investigative [1587926]
Formula
C31H34BrClN6O2
Canonical SMILES
Clc1ccc2C(N3CCN(C(C3)C(=O)NCc4cccnc4)C(=O)NC5CCCC5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C31H34BrClN6O2/c32-23-14-22-8-7-21-15-24(33)9-10-26(21)29(28(22)35-18-23)38-12-13-39(31(41)37-25-5-1-2-6-25)27(19-38)30(40)36-17-20-4-3-11-34-16-20/h3-4,9-11,14-16,18,25,27,29H,1-2,5-8,12-13,17,19H2,(H,36,40)(H,37,41)
InChIKey
UZOLOYJCNMNVOM-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.