Drug Information

Drug General Information
Drug ID
DXPE9S
Drug Name
4-(3-Chloro-phenyl)-6-[(4-chloro-phenyl)-hydroxy-(4-methyl-4H-[1,2,4]triazol-3-yl)-methyl]-1H-quinolin-2-one
Synonyms
CHEMBL422815
Indication Discovery agent Investigative [1587926]
Formula
C25H18Cl2N4O2
Canonical SMILES
Cn1cnnc1C(O)(c2ccc(Cl)cc2)c3ccc4nc(O)cc(c5cccc(Cl)c5)c4c3
InChI
InChI=1S/C25H18Cl2N4O2/c1-31-14-28-30-24(31)25(33,16-5-8-18(26)9-6-16)17-7-10-22-21(12-17)20(13-23(32)29-22)15-3-2-4-19(27)11-15/h2-14,33H,1H3,(H,29,32)
InChIKey
JQFVATYKOSELCB-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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