Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXQ0ST
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| Drug Name |
N-(2-methoxy-5-(trifluoromethyl)phenyl)-4-methyl-3-(3-(pyrimidin-4-yl)pyridin-2-ylamino)benzamide
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| Synonyms |
CHEMBL219996
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H20F3N5O2
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| Canonical SMILES |
COc1ccc(cc1NC(=O)c2ccc(C)c(Nc3ncccc3c4ccncn4)c2)C(F)(F)F
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| InChI |
InChI=1S/C25H20F3N5O2/c1-15-5-6-16(24(34)33-21-13-17(25(26,27)28)7-8-22(21)35-2)12-20(15)32-23-18(4-3-10-30-23)19-9-11-29-14-31-19/h3-14H,1-2H3,(H,30,32)(H,33,34)
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| InChIKey |
VHCQYUCVMXQFBY-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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