Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXQU1P
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| Drug Name |
5-Methyl-1-phenyl-1H-pyrazole-4-carboxylic acid {(S)-2-cyclohexyl-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-ethyl}-amide
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| Synonyms |
CHEMBL372642
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H37N5O3
|
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| Canonical SMILES |
COc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c3cnn(c3C)c4ccccc4)cc1
|
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| InChI |
InChI=1S/C29H37N5O3/c1-21-26(20-32-34(21)24-11-7-4-8-12-24)28(35)33-27(19-22-9-5-3-6-10-22)29(36)31-18-17-30-23-13-15-25(37-2)16-14-23/h4,7-8,11-16,20,22,27,30H,3,5-6,9-10,17-19H2,1-2H3,(H,31,36)(H,33,35)/t27-/m0/s1
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| InChIKey |
SOLUSPIOJGWVKG-MHZLTWQESA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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