Drug Information

Drug General Information
Drug ID
DXR1AR
Drug Name
2-(4-Bromo-phenyl)-1-[4-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-ethanone
Synonyms
CHEMBL171443
Indication Discovery agent Investigative [1587926]
Formula
C26H25BrClN3O
Canonical SMILES
Clc1ccc2C(N3CCN(CC3)C(=O)Cc4ccc(Br)cc4)c5ncccc5CCc2c1
InChI
InChI=1S/C26H25BrClN3O/c27-21-7-3-18(4-8-21)16-24(32)30-12-14-31(15-13-30)26-23-10-9-22(28)17-20(23)6-5-19-2-1-11-29-25(19)26/h1-4,7-11,17,26H,5-6,12-16H2
InChIKey
DNMVTJNZEPUZGW-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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